Anti-PITRM1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-453A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A305-453A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: ATP-independent protease that degrades mitochondrial transit peptides after... more

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Product information "Anti-PITRM1"

Protein function: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. [The UniProt Consortium]

Keywords:	Anti-hMP1, Anti-hPreP, Anti-PITRM1, Anti-KIAA1104, EC=3.4.24.-, Anti-Metalloprotease 1, Anti-Pitrilysin metalloproteinase 1, Anti-Presequence protease, mitochondrial
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-453A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: X. tropicalis)
Immunogen:	synthetic peptide. The epitope recognized by A305-453A-T maps to a region between residue 987 to 1037 of human Presequence protease, mitochondrial using the numbering given in entry Q5JRX3.3 (GeneID 10531).
Format:	Antigen Affinity Purified