Anti-PIK3R2

Anti-PIK3R2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-593A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-593A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-593A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that... more
Product information "Anti-PIK3R2"
Protein function: Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5- trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin- dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement. [The UniProt Consortium]
Keywords: Anti-PIK3R2, Anti-PI3-kinase subunit p85-beta, Anti-PI3K regulatory subunit beta, Anti-PI3-kinase regulatory subunit beta, Anti-PtdIns-3-kinase regulatory subunit beta, Anti-PtdIns-3-kinase regulatory subunit p85-beta
Supplier: Bethyl Laboratories
Supplier-Nr: A302-593A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating Macaque, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-593A-T maps to a region between residue 75 and 125 of human phosphoinositide-3-kinase, regulatory subunit 2 using the numbering given in entry NP_005018.1 (GeneID 5296).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-PIK3R2"
Write a review
or to review a product.
Viewed