Anti-PIAS4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-DM9	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-PIAS4 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-PIAS4"

Anti-PIAS4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PIAS4 from other sources has not been determined. Protein function: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation. [The UniProt Consortium]

Keywords:	Anti-PIASy, Anti-PIAS4, Anti-PIASG, EC=6.3.2.-, Anti-PIAS-gamma, Anti-E3 SUMO-protein ligase PIAS4, Anti-Protein inhibitor of activated STAT protein 4, Anti-Protein inhibitor of activated STAT protein gamma
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-DM9

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	19 amino acid synthetic peptide near the N-terminus of human PIAS4.
Format:	Purified