Anti-PHC3

Anti-PHC3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES10019.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES10019.100 100 µl - -

10 - 14 business days*

290.00€
 
function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to... more
Product information "Anti-PHC3"
function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2., Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Nucleus .
Keywords: Anti-PHC3, Anti-EDR3, Anti-hPH3, Anti-Homolog of polyhomeotic 3, Anti-Polyhomeotic-like protein 3, Anti-Early development regulatory protein 3, PHC3 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES10019

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human protein . at AA range: 720-800
MW: 108 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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