Anti-PFKL

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG42147.100 100 µl - -

10 - 15 business days*

616.00€
 
Protein function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose... more
Product information "Anti-PFKL"
Protein function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway. [The UniProt Consortium]
Keywords: Anti-PFK-L, Anti-PFK-B, Anti-ATP-PFK, Anti-Phosphohexokinase, Anti-6-phosphofructokinase type B, Anti-Phosphofructo-1-kinase isozyme B, Anti-ATP-dependent 6-phosphofructokinase, liver type
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG42147

Properties

Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: KLH-conjugated synthetic peptide between aa. 669-699 of Human PFKL
MW: 85 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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