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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V2601-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V2601-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb specifically precipitates... more
Product information "Anti-Perlecan (Large), clone SPM255"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Protein function: Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development. [The UniProt Consortium]
Keywords: | Anti-HSPG2, Perlecan Antibody (Large) |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V2601 |
Properties
Application: | FC, IF, IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | SPM255 |
Conjugate: | No |
Host: | Rat |
Species reactivity: | human, monkey, bovine, swine, mouse, fish |
Immunogen: | Murine EHS laminin preparation |
Format: | Purified |
Database Information
KEGG ID : | K06255 | Matching products |
UniProt ID : | P98160 | Matching products |
Gene ID | GeneID 3339 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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