Anti-PDL1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-101-GU8	100 µg		-	-	6 - 10 business days*		684.00€

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This affinity purified antibody is directed against human PDL1. This product was affinity... more

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Product information "Anti-PDL1"

This affinity purified antibody is directed against human PDL1. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077). [The UniProt Consortium]

Keywords:	Anti-B7H1, Anti-CD274, Anti-B7-H1, Anti-PD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-101-GU8

Properties

Application:	ELISA, FC, IHC, IFM, IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human, mouse
Immunogen:	synthetic peptide corresponding to an internal portion of human PDL1 conjugated to Keyhole Limpet Hemocyanin (KLH).
Format:	Purified