Anti-PDE12

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG10789.50	50 µg		-	-	6 - 14 business days*		575.00€

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Protein function: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the... more

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Product information "Anti-PDE12"

Protein function: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system. [The UniProt Consortium]

Keywords:	Anti-PDE12, Anti-2-PDE, Anti-2'-PDE, EC=3.1.4.-, EC=3.1.13.4, Anti-Mitochondrial deadenylase, Anti-2',5'-phosphodiesterase 12
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG10789

Properties

Application:	ELISA, IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, monkey, rat
Immunogen:	Synthetic peptide taken within aa. 570-620 from Human PDE12
Format:	Affinity Purified