Anti-Pdcd4 Ready-To-Use

Anti-Pdcd4 Ready-To-Use
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-965-RTU 100 µl - -

6 - 10 business days*

439.00€
 
RTU Anti-Pdcd4 affinity purified antibody is directed against human Pdcd4 protein. The product... more
Product information "Anti-Pdcd4 Ready-To-Use"
RTU Anti-Pdcd4 affinity purified antibody is directed against human Pdcd4 protein. The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.  A BLAST analysis was used to suggest cross-reactivity with Pdcd4 from human, mouse, rat and Xenopus based on 100% homology with the immunizing sequence.  Cross-reactivity with Pdcd4 from other sources has not been determined. The antibody reacts with Pdcd4 protein that is either phosphorylated or non-phosphorylated at Ser457. Protein function: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA. [The UniProt Consortium]
Keywords: Anti-H731, Anti-PDCD4, Anti-Protein 197/15a, Anti-Nuclear antigen H731-like, Anti-Programmed cell death protein 4, Anti-Neoplastic transformation inhibitor protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-965-RTU

Properties

Application: ELISA, IHC, IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat, Xenopus
Immunogen: synthetic peptide corresponding amino acids near the carboxyl terminus of human Pdcd4 protein.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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