Anti-PC, NT (PC, Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase)

Anti-PC, NT (PC, Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039714.200 200 µl - -

1 - 19 business days

557.00€
 
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the... more
Product information "Anti-PC, NT (PC, Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase)"
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PC, Anti-PCB, EC=6.4.1.1, Anti-Pyruvic carboxylase, Anti-Pyruvate carboxylase, mitochondrial
Supplier: United States Biological
Supplier-Nr: 039714

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Mouse
Immunogen: PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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