Anti-PAX6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F42570-0.08ML 80 µl - -

3 - 10 business days*

326.00€
NSJ-F42570-0.4ML 400 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes paired box gene 6, one of many... more
Product information "Anti-PAX6"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq]. Protein function: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Isoform 5a appears to function as a molecular switch that specifies target genes. [The UniProt Consortium]
Keywords: Anti-AN2, Anti-PAX6, Anti-Oculorhombin, Anti-Aniridia type II protein, Anti-Paired box protein Pax-6, Anti-PAX6 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: F42570

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: This anti-PAX6 antibody was produced from rabbits immunized with a recombinant protein from human PAX6.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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