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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay13557-1 | 1 each | - |
6 - 10 business days* |
481.00€
|
The poly(ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as... more
Product information "Anti-PARP (Cleaved)"
The poly(ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.Immunogen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP. Formulation: (Request formulation change), 100 µg protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Host: Mouse. Isotype: IgG2bkappa. Applications: WB and FC (intracellular). Origin: Animal/Mouse.
Keywords: | Anti-ADPRT, Anti-PARP1, Anti-PARP-1, EC=2.4.2.30, Anti-ADPRT 1, Anti-Poly[ADP-ribose] synthase 1, Anti-Poly [ADP-ribose] polymerase 1, Anti-NAD(+) ADP-ribosyltransferase 1 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 13557 |
Properties
Application: | WB, FC (intracellular) |
Antibody Type: | Monoclonal |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP |
Format: | Purified |
Database Information
KEGG ID : | K24070 | Matching products |
UniProt ID : | P09874 | Matching products |
Gene ID | GeneID 142 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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