Anti-PARP-1 [ARTD1] (human)

Anti-PARP-1 [ARTD1] (human)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-25T-0002-R100 100 µl -

3 - 9 business days*

10 %
242.00€
217.80€
 
Recognizes human PARP-1. Cross-reacts weakly with mouse and monkey PARP-1. Liquid. From rabbit.... more
Product information "Anti-PARP-1 [ARTD1] (human)"
Recognizes human PARP-1. Cross-reacts weakly with mouse and monkey PARP-1. Liquid. From rabbit. PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Keywords: Anti-PPOL, Anti-ADPRT, Anti-ARTD1, Anti-PARP1, Anti-PARP-1, EC=2.4.2.30, Anti-ADPRT 1, Anti-Poly[ADP-ribose] synthase 1, Anti-Poly [ADP-ribose] polymerase 1, Anti-NAD(+) ADP-ribosyltransferase 1, Anti-ADP-ribosyltransferase diphtheria toxin-like 1
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-25T-0002

Properties

Application: ICC, IHC, IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, monkey, mouse
Immunogen: Recombinant human PARP-1 [ARTD1] (aa 215-525).

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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