Anti-PARD3

Item number	Size	Manual	Delivery time	Price
A304-496A-T	20 µl (2 blots)	-	3 - 9 business days*	131.00€
A304-496A-M	100 µl (10 blots)	-	3 - 9 business days*	313.00€
A304-496A	100 µl (100 µg)	-	3 - 9 business days*	465.00€

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Protein function: Adapter protein involved in asymmetrical cell division and cell polarization... more

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Product information "Anti-PARD3"

Protein function: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons. [The UniProt Consortium]

Keywords:	Anti-ASIP, Anti-PAR3, Anti-PAR-3, Anti-PARD3, Anti-PARD-3, Anti-PAR3-alpha, Anti-CTCL tumor antigen se2-5, Anti-Partitioning defective 3 homolog, Anti-Atypical PKC isotype-specific-interacting protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-496A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Reactivity:	Human, Mouse (Expected: Rat)
Immunogen:	synthetic peptide. The epitope recognized by A304-496A-T maps to a region between residue 1306 to 1356 of human Par-3 Partitioning Defective 3 Homolog using the numbering given in entry NP_062565.2 (GeneID 56288).
Format:	Antigen Affinity Purified