Anti-PAPPA

Item number	Size	Manual	Delivery time	Price
E-AB-13489.20	20 µl	-	7 - 16 business days*	89.00€
E-AB-13489.60	60 µl	-	7 - 16 business days*	174.00€
E-AB-13489.120	120 µl	-	7 - 16 business days*	292.00€
E-AB-13489.200	200 µl	-	7 - 16 business days*	485.00€

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This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding... more

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Product information "Anti-PAPPA"

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. Protein function: Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. [The UniProt Consortium]

Keywords:	Anti-PAPPA, Anti-PAPP-A, Anti-IGFBP-4ase, EC=3.4.24.79, Anti-Pappalysin-1, Anti-IGF-dependent IGFBP-4 protease, Anti-Pregnancy-associated plasma protein A, Anti-Insulin-like growth factor-dependent IGF-binding protein 4 protease, PAPPA Polyclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-13489

Properties

Application:	IHC, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthetic peptide of human PAPPA
Format:	Purified