Anti-Papillomavirus 16 E7, clone 716-281

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG10164.50	50 µg		-	-	6 - 14 business days*		436.00€
ARG10164.100	100 µg		-	-	6 - 14 business days*		624.00€

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Protein function: Plays a role in viral genome replication by driving entry of quiescent cells... more

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Product information "Anti-Papillomavirus 16 E7, clone 716-281"

Protein function: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha. [The UniProt Consortium]

Keywords:	Anti-Protein E7
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG10164

Properties

Application:	ELISA, WB
Antibody Type:	Monoclonal
Clone:	716-281
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	HPV oncoprotein E7, types 16 & 18
Format:	Purified