Anti-Pan Cytokeratin Cocktail, clone AE1 + AE3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2330SAF-100UG 100 µg - -

3 - 10 business days*

1 mg/ml in sterile PBS, BSA free, sodium azide free. Twenty human keratins are resolved with... more
Product information "Anti-Pan Cytokeratin Cocktail, clone AE1 + AE3"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This pan keratin antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3-6, CK8, CK10, CK14-16, and CK19. Many studies have shown the usefulness of cytokeratin markers in cancer research and tumor diagnosis. The AE1 + AE3 antibody cocktail is a broad spectrum pan cytokeratin antibody cocktail which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. It stains cytokeratin present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas. Protein function: May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. [The UniProt Consortium]
Keywords: Anti-K1, Anti-KRT1, Anti-KRTA, Anti-CK-1, Anti-Keratin-1, Anti-Cytokeratin-1, Anti-Hair alpha protein, Anti-67 kDa cytokeratin, Anti-Type-II keratin Kb1, Anti-Keratin, type II cytoskeletal 1, Pan Cytokeratin Antibody Cocktail
Supplier: NSJ Bioreagents
Supplier-Nr: V2330SAF


Application: WB, FC, IHC, IF
Antibody Type: Mixed
Clone: AE1+AE3
Conjugate: No
Host: Mouse
Reactivity: Human, Monkey, Bovine, Dog, Rabbit, Mouse, Rat, Chicken
Immunogen: Human epidermal keratin was used as the immunogen for this pan Cytokeratin antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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