Anti-p63

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG10654.50 50 µg - -

6 - 14 business days*

528.00€
 
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor.... more
Product information "Anti-p63"
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [The UniProt Consortium]
Keywords: Anti-p51, Anti-p63, Anti-KET, Anti-p40, Anti-p73L, Anti-TP63, Anti-CUSP, Anti-Tumor protein 63, Anti-Tumor protein p73-like, Anti-Transformation-related protein 63, Anti-Keratinocyte transcription factor KET, Anti-Chronic ulcerative stomatitis protein
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG10654

Properties

Application: ICC, IF, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide around aa. 82-98 of Human p63. (DMDARRNKQQRIKEEGE)
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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