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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A304-790A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A304-790A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: This multifunctional protein catalyzes the formation, breakage and... more
Product information "Anti-P4HB/PDI"
Protein function: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9, the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). [The UniProt Consortium]
Keywords: | Anti-p55, Anti-PDI, Anti-P4HB, Anti-ERBA2L, EC=5.3.4.1, Anti-Protein disulfide-isomerase, Anti-Prolyl 4-hydroxylase subunit beta, Anti-Cellular thyroid hormone-binding protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A304-790A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat, bovine, orangutan) |
Immunogen: | synthetic peptide. The epitope recognized by A304-790A-T maps to a region between residue 50 to 100 of human Prolyl 4-Hydroxylase, Beta Polypeptide using the numbering given in entry P07237 (GeneID 5034). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K09580 | Matching products |
UniProt ID : | P07237 | Matching products |
Gene ID | GeneID 5034 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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