Anti-p35

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-ME9S 25 µl - -

6 - 10 business days*

180.00€
 
This affinity purified antibody is directed against mouse p35/Cdk5.  This product was affinity... more
Product information "Anti-p35"
This affinity purified antibody is directed against mouse p35/Cdk5.  This product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to rat, human, bovine, and Spermophilus citellus. Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. [The UniProt Consortium]
Keywords: Anti-Cdk5r, Anti-Cdk5r1
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-ME9S

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: synthetic peptide corresponding to a near N-terminal portion of mouse p35/Cdk5 conjugated to Keyhole Limpet Hemocyanin (KLH).
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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