Anti-p21/CIP1/CDKN1A Recombinant Monoclonal

Anti-p21/CIP1/CDKN1A Recombinant Monoclonal
%
Discount Promotion
Promotion:

Save 20% on selected monoclonal antbodies from Bethyl Laboratories! *Trial sizes are excluded*

*1
*1 Offer expires 30/06/2026
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
A700-337CF 100 µg -

2 - 8 business days*

20 %
1,075.00€
860.00€
 
Protein function: May be involved in p53/TP53 mediated inhibition of cellular proliferation in... more
Product information "Anti-p21/CIP1/CDKN1A Recombinant Monoclonal"
Protein function: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin- dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D- CDK4 complex. Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding (PubMed:11595739). Plays an important role in controlling cell cycle progression and DNA damage- induced G2 arrest (PubMed:9106657). [The UniProt Consortium]
Keywords: Anti-p21, Anti-MDA-6, Anti-CAP20, Anti-CDKN1A, Anti-CDK-interacting protein 1, Anti-Cyclin-dependent kinase inhibitor 1, Anti-Melanoma differentiation-associated protein 6
Supplier: Bethyl Laboratories
Supplier-Nr: A700-337CF

Properties

Application: WB, IP, IHC, ICC
Antibody Type: Monoclonal
Clone: BLR337M
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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