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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P0999-60B.100 | 100 µg | - | - |
3 - 19 business days* |
916.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
p15INK4B is an ~15kD member of the p16INK4 family. Human p15INK4B is 138aa in length and contains... more
Product information "Anti-p15INK4b (Cyclin-dependent Kinase 4 Inhibitor B, Multiple Tumor Suppressor 2, MTS-2, p14-INK4b,"
p15INK4B is an ~15kD member of the p16INK4 family. Human p15INK4B is 138aa in length and contains four ankyrin repeats, a common structural sequence found in members of the INK4 family. The first 50aa of p15INK4B share 44% sequence identity with p16INK4. Following this is an 81aa region sharing 97% sequence identity, after which the two proteins diverge. Human p15INK4B shares 83% aa sequence identity with mouse and rat p15INK4B. Functionally, p15INK4B interacts strongly with CDK4 and CDK6 and is a potent inhibitor. p15INK4B can potentially induce cell cycle arrest by acting as an effector of TGF-B. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-MTS2, Anti-MTS-2, Anti-CDKN2B, Anti-p15INK4B, Anti-p15-INK4b, Anti-p14-INK4b, Anti-Multiple tumor suppressor 2, Anti-Cyclin-dependent kinase 4 inhibitor B |
Supplier: | United States Biological |
Supplier-Nr: | P0999-60B |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 12K152 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa2-138 from human p15INK4b expressed in E.coli. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04685 | Matching products |
UniProt ID : | P42772 | Matching products |
Gene ID | GeneID 1030 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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