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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F40192-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F40192-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. p100 is a spindle assembly factor. Required for... more
Product information "Anti-p100 (TPX2), clone 19AT738.292"
In 1X PBS, pH 7.4, with 0.09% sodium azide. p100 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. [UniProt] Protein function: Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin- alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940). [The UniProt Consortium]
Keywords: | Anti-p100, Anti-TPX2, Anti-DIL-2, Anti-C20orf1, Anti-Protein fls353, Anti-Targeting protein for Xklp2, Anti-Hepatocellular carcinoma-associated antigen 90, Anti-Hepatocellular carcinoma-associated antigen 519, p100 Antibody (TPX2) |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F40192 |
Properties
Application: | WB, ELISA |
Antibody Type: | Monoclonal |
Clone: | 19AT738.292 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | A KLH conjugated synthetic peptide from the human protein was used as immunogen for this p100 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K16812 | Matching products |
UniProt ID : | Q9ULW0 | Matching products |
Gene ID | GeneID 22974 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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