Anti-Osteoblast Specific Factor 2 (OSF-2, Periostin, Fasciclin-I like)

Anti-Osteoblast Specific Factor 2 (OSF-2, Periostin, Fasciclin-I like)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
O8057-06A.100 100 µg - -

3 - 19 business days

742.00€
 
Periostin, a disulfide-linked 90kD, 811aa protein was originally isolated as an... more
Product information "Anti-Osteoblast Specific Factor 2 (OSF-2, Periostin, Fasciclin-I like)"
Periostin, a disulfide-linked 90kD, 811aa protein was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta-1 (TGFbeta1) and bone morphogenetic protein (BMP)-2. OSF-2 has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-1ug/ml Detects ~1ng/well of rhOSF-2. Cross-reactivity with rmOSF-2 ~45% . , Western Blot: 0.1-0.2ug/ml Detects ~25ng/lane of rhOSF-2 under non-reducing and reducing conditions. , Optimal dilutions to be determined by the researcher. Endotoxin: < 0.1EU/ug (LAL) , Storage and Stability:, Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, PBS. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: O8057-06A

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human
Immunogen: NS0-derived rhOSF-2.
Format: Affinity Purified

Database Information

UniProt ID : Q15063 | Find alternatives
Gene ID GeneID 10631 | Find alternatives

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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