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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA039227.25 | 25 µl | - |
3 - 8 business days* |
330.00€
|
|||
| ATA-HPA039227.100 | 100 µl | - |
3 - 8 business days* |
463.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Lipid transporter involved in lipid countertransport between the Golgi complex... more
Product information "Anti-OSBP"
Protein function: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25- hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 97%
| Keywords: | Anti-OSBP1, Anti-Oxysterol-binding protein 1 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA039227 |
Properties
| Application: | ICC, IHC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HLERAFRGAT VLPANTPGNV GSGKDQCCSG KGDMSDEDDE NEFFDAPEII TMPENLGHKR TGSNISGASS DISLDEQYKH QLEETKKEKR TRIPYKP (ATA-APrEST80518) |
Database Information
| KEGG ID : | K20456 | Matching products |
| UniProt ID : | P22059 | Matching products |
| Gene ID : | GeneID 5007 | Matching products |
| Protein Atlas Nr. : | ENSG00000110048 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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