Anti-OSBP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-554A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A304-554A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Lipid transporter involved in lipid countertransport between the Golgi complex... more

Close menu

Product information "Anti-OSBP"

Protein function: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749). [The UniProt Consortium]

Keywords:	Anti-OSBP1, Anti-Oxysterol-binding protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-554A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rabbit)
Immunogen:	synthetic peptide. The epitope recognized by A304-554A-T maps to a region between residue 740 to 790 of human Oxysterol Binding Protein using the numbering given in entry NP_002547.1 (GeneID 5007).
Format:	Antigen Affinity Purified