Anti-OSB11

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008], Protein function: Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25- hydroxycholesterol (PubMed:17428193). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Late endosome membrane . Golgi apparatus, trans-Golgi network membrane . Localizes at the Golgi-late endosome interface.