Anti-ORP3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-557A-T 10 µl (10 µg) -

2 - 8 business days*

165.00€
A304-557A 100 µl (100 µg) -

2 - 8 business days*

586.00€
 
Protein function: Phosphoinositide-binding protein which associates with both cell and... more
Product information "Anti-ORP3"
Protein function: Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes (PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments (PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology (PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion (PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3 (PubMed:16143324). Also binds 25- hydroxycholesterol and cholesterol (PubMed:17428193). [The UniProt Consortium]
Keywords: Anti-ORP-3, Anti-OSBPL3, Anti-KIAA0704, Anti-OSBP-related protein 3, Anti-Oxysterol-binding protein-related protein 3
Supplier: Bethyl Laboratories
Supplier-Nr: A304-557A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: orangutan, gorilla, chimpanzee, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A304-557A-T maps to a region between residue 456 to 506 of human Oxysterol Binding Protein-Like 3 using the numbering given in entry NP_056365.1 (GeneID 26031).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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