Anti-OLFM2

Anti-OLFM2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA057771.25 25 µl -

3 - 8 business days*

369.00€
ATA-HPA057771.100 100 µl -

3 - 8 business days*

491.00€
 
Protein function: Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle... more
Product information "Anti-OLFM2"
Protein function: Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes (PubMed:25298399). Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-NOE2, Anti-OLFM2, Anti-Noelin-2, Anti-Olfactomedin-2
Supplier: Atlas Antibodies
Supplier-Nr: HPA057771

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SLFYNKYQSN VVVKYHFRSR SVLVQRSLPG AGYNNTFPYS WGGFSDMDFM VDES (ATA-APrEST82565)

Database Information

UniProt ID : O95897 | Matching products
Gene ID : GeneID 93145 | Matching products
Protein Atlas Nr. : ENSG00000105088

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-OLFM2"
Write a review
or to review a product.
Viewed