Anti-OGDH

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40529.100	100 µl		-	-	6 - 14 business days*		707.00€

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Protein function: 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate... more

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Product information "Anti-OGDH"

Protein function: 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate (PubMed:24495017). The 2- oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (PubMed:24495017). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (PubMed:29211711). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (PubMed:29211711). [The UniProt Consortium]

Keywords:	Anti-OGDH, Anti-OGDC-E1, Anti-Alpha-ketoglutarate dehydrogenase, Anti-2-oxoglutarate dehydrogenase, mitochondrial, Anti-2-oxoglutarate dehydrogenase complex component E1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40529

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant fusion protein corresponding to aa. 148-427 of Human OGDH (NP_001003941.1)
MW:	115 kD
Format:	Affinity Purified