Protein function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. [The UniProt Consortium]
Anti-OCT1, Anti-Oct-1, Anti-OTF-1, Anti-NF-A1, Anti-POU2F1, Anti-Octamer-binding protein 1, Anti-Octamer-binding transcription factor 1, Anti-POU domain, class 2, transcription factor 1
Human, Mouse (Expected: Rat, X. Laevis, X. Tropicalis, Chicken, Pig)
synthetic peptide. The epitope recognized by A301-716A-T maps to a region between residue 250 and 300 of human octamer-binding transcription factor 1 using the numbering given in entry NP_002688.2 (GeneID 5451).