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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA009291.25 | 25 µl | - |
7 - 10 business days* |
358.00€
|
|||
| ATA-HPA009291.100 | 100 µl | - |
7 - 10 business days* |
477.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC... more
Product information "Anti-OAZ1"
Protein function: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin- independent proteolytic destruction by the 26S proteasome (PubMed:17900240, PubMed:26305948, PubMed:26443277). Triggers ODC degradation by inducing the exposure of a cryptic proteasome- interacting surface of ODC (PubMed:26305948). Stabilizes AZIN2 by interfering with its ubiquitination (PubMed:17900240). Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (PubMed:12097147). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 81%
| Keywords: | Anti-AZ1, Anti-OAZ, Anti-OAZ1, Anti-ODC-Az, Anti-Ornithine decarboxylase antizyme 1 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA009291 |
Properties
| Application: | IHC, ICC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: QSRLTDAKRI NWRTVLSGGS LYIEIPGGAL PEGSKDSFAV LLEFAEEQLR ADHVFICFHK NREDRAALLR TFSFLGFEIV RPGHPLVPKR PDACFMAYTF ERESSGEEEE (ATA-APrEST71204) |
Database Information
| KEGG ID : | K16548 | Matching products |
| UniProt ID : | P54368 | Matching products |
| Gene ID : | GeneID 4946 | Matching products |
| Protein Atlas Nr. : | ENSG00000104904 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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