Anti-NXF1

Anti-NXF1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA064429.25 25 µl

7 - 10 business days*

369.00€
ATA-HPA064429.100 100 µl

7 - 10 business days*

491.00€
 
Rabbit Polyclonal NXF1 Antibody against Human nuclear RNA export factor 1. Validated for Western... more
Product information "Anti-NXF1"
Rabbit Polyclonal NXF1 Antibody against Human nuclear RNA export factor 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000010097: 88%, ENSRNOG00000019069: 93%. Protein function: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway) (PubMed:10924507). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex (PubMed:18364396, PubMed:19165146, PubMed:9660949). ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export (PubMed:18364396, PubMed:19165146, PubMed:9660949). Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244). [The UniProt Consortium]
Keywords: Anti-TAP, Anti-NXF1, Anti-Tip-associated protein, Anti-mRNA export factor TAP, Anti-Tip-associating protein, Anti-Nuclear RNA export factor 1
Supplier: Atlas Antibodies
Supplier-Nr: HPA064429

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: FTPIEFHYEN TRAQFFVEDA STASALKAVN YKILDRENRR ISIIINSSAP PHTILNELKP EQVEQLKLIM SKRYDGSQQA LDLKGLRSDP
Format: Affinity Purified

Handling & Safety

Storage: -20°C (+4 °C for short term storage)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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