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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG44377.100 | 100 µl | - | - |
6 - 14 business days* |
707.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP,... more
Product information "Anti-NUDT15"
Protein function: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (PubMed:22556419, PubMed:26238318). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:26238318, PubMed:22556419). Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (PubMed:26238318, PubMed:25108385). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (PubMed:19419956). [The UniProt Consortium]
| Keywords: | Anti-MTH2, Anti-MTH2, Anti-MutT homolog 2, Anti-Nudix motif 15, Anti-MutT homolog 2, Anti-Nudix motif 15, Anti-Nudix hydrolase 15, Anti-Nudix hydrolase 15, Anti-Nucleotide triphosphate diphosphatase NUDT15, Anti-Nucleotide triphosphate diphosphatase NUDT1 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG44377 |
Properties
| Application: | IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 |
| MW: | 19 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K03574 | Matching products |
| UniProt ID : | Q9NV35 | Matching products |
| Gene ID : | GeneID 55270 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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