Anti-NUD15

Anti-NUD15
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES18880.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES18880.100 100 µl - -

10 - 14 business days*

290.00€
 
Protein function: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP,... more
Product information "Anti-NUD15"
Protein function: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (PubMed:22556419, PubMed:26238318). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:26238318, PubMed:22556419). Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (PubMed:26238318, PubMed:25108385). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (PubMed:19419956). Exhibits decapping activity towards dpCoA-capped RNAs in vitro. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization:
Keywords: Anti-MTH2, Anti-Nudix motif 15, Anti-MutT homolog 2, Anti-Nudix hydrolase 15, Anti-Nucleotide triphosphate diphosphatase NUDT15, Anti-Nucleoside diphosphate-linked moiety X motif 15, Anti-Nucleoside diphosphate-linked to another moiety X hydrolase 15, NUD
Supplier: ELK Biotechnology
Supplier-Nr: ES18880

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human NUD15 AA range: 62-112
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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