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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
030506.100 | 100 µl | - | - |
3 - 19 business days* |
644.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Nucleophosmin (NPM), also named B23 or NO38, is a major nucleolar protein which is 20 times more... more
Product information "Anti-Nucleophosmin"
Nucleophosmin (NPM), also named B23 or NO38, is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. NPM has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., Immunofluorescence: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-NPM, Anti-NPM1, Anti-Numatrin, Anti-Nucleophosmin, Anti-Nucleolar protein NO38, Anti-Nucleolar phosphoprotein B23 |
Supplier: | United States Biological |
Supplier-Nr: | 030506 |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 13B584 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, monkey |
Immunogen: | Purified recombinant fragment of human NPM expressed in E. coli. |
Database Information
KEGG ID : | K11276 | Matching products |
UniProt ID : | P06748 | Matching products |
Gene ID | GeneID 4869 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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