Anti-NSUN5

Anti-NSUN5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES10073.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES10073.100 100 µl - -

10 - 14 business days*

290.00€
 
This gene encodes a member of an evolutionarily conserved family of proteins that may function as... more
Product information "Anti-NSUN5"
This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013], Protein function: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA (PubMed:23913415, PubMed:31428936, PubMed:31722427). m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity (PubMed:31428936, PubMed:31722427). Required for corpus callosum and cerebral cortex development. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Nucleus, nucleolus .
Keywords: Anti-NOL1R, Anti-NOL1-related protein, Anti-NOL1/NOP2/Sun domain family member 5, Anti-28S rRNA (cytosine-C(5))-methyltransferase, Anti-Williams-Beuren syndrome chromosomal region 20A protein, NSUN5 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES10073

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human protein . at AA range: 320-400
MW: 47 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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