Anti-NSFL1C

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40146.100	100 µl		-	-	6 - 14 business days*		616.00€

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Protein function: Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi... more

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Product information "Anti-NSFL1C"

Protein function: Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro) (PubMed:15498563). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PubMed:23649807). Also, regulates spindle orientation during mitosis (PubMed:23649807). [The UniProt Consortium]

Keywords:	Anti-NSFL1C, Anti-UBXN2C, Anti-p97 cofactor p47, Anti-NSFL1 cofactor p47, Anti-UBX domain-containing protein 2C
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40146

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	KLH-conjugated synthetic peptide between aa. 214-248 of Human NSFL1C
MW:	40.5 kD
Format:	Purified