Anti-NRARP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES10964.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES10964.100	100 µl		-	-	10 - 14 business days*		290.00€

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function:May play a role in the formation of somites.,similarity:Belongs to the NRARP... more

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Product information "Anti-NRARP"

function:May play a role in the formation of somites.,similarity:Belongs to the NRARP family.,similarity:Contains 2 ANK repeats., Protein function: Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737). Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis (PubMed:19154719). During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior- posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD) and down-regulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization:

Keywords:	Anti-NRARP, Anti-Notch-regulated ankyrin repeat-containing protein, NRARP rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES10964

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from part region of human protein AA range: 1-50
MW:	12 kD
Format:	Purified