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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG45651.50 | 50 µg | - | - |
10 - 15 business days* |
501.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcriptional regulator that acts as a negative regulator of... more
Product information "Anti-NR0B2"
Protein function: Transcriptional regulator that acts as a negative regulator of receptor-dependent signaling pathways (PubMed:8650544). Specifically inhibits transactivation of the nuclear receptor with which it interacts (PubMed:8650544). Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1. Essential component of the liver circadian clock which via its interaction with NR1D1 and RORG regulates NPAS2- mediated hepatic lipid metabolism (PubMed:25212631). Regulates the circadian expression of cytochrome P450 (CYP) enzymes (PubMed:30555544). Represses: NR5A2 and HNF4A to down-regulate CYP2C38, NFLI3 to up-regulate CYP2A5, BHLHE41/HNF1A axis to up-regulate CYP1A2, CYP2E1 and CYP3A11, and NR1D1 to up-regulate CYP2B10, CYP4A10 and CYP4A14 (PubMed:30555544). [The UniProt Consortium]
| Keywords: | Anti-Shp, Anti-Nr0b2, Anti-Small heterodimer partner, Anti-Small heterodimer partner, Anti-Orphan nuclear receptor SHP, Anti-Orphan nuclear receptor SHP, Anti-Nuclear receptor subfamily 0 group B member 2, Anti-Nuclear receptor subfamily 0 group B member |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG45651 |
Properties
| Application: | FC, ICC, IF, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | mouse, rat |
| Immunogen: | Recombinant protein containing to mouse NR0B2 |
| MW: | 29 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K08563 | Matching products |
| UniProt ID : | Q62227 | Matching products |
| Gene ID : | GeneID 23957 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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