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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA048743.25 | 25 µl | - |
7 - 10 business days* |
300.00€
|
|||
ATA-HPA048743.100 | 100 µl | - |
7 - 10 business days* |
421.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2... more
Product information "Anti-NOTCH2"
Protein function: Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus (PubMed:21378985, PubMed:21378989). Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation (PubMed:29149593). Positively regulates self-renewal of liver cancer cells (PubMed:25985737). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 86%
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA048743 |
Properties
Application: | ICC, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PGILQASPNP MLATAAPPAP VHAQHALSFS NLHEMQPLAH GASTVLPSVS QLLSHHHIVS PGSGSAGSLS RLHPVPVPAD WMNRMEVNET QYNEMFGMVL APAEGTHPGI APQSRPPEGK HITTPREPLP PIVTFQLIPK GSIAQ (ATA-APrEST88601) |
Database Information
KEGG ID : | K20994 | Matching products |
UniProt ID : | Q04721 | Matching products |
Gene ID : | GeneID 4853 | Matching products |
Protein Atlas Nr. : | ENSG00000134250 |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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