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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-DD3 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-NogoA Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-NogoA"
Anti-NogoA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least five isoforms of Nogo are known to exist, this antibody is specific for NogoA. Protein function: Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing. [The UniProt Consortium]
Keywords: | Anti-NSP, Anti-RTN4, Anti-My043, Anti-RTN-x, Anti-Foocen, Anti-KIAA0886, Anti-Reticulon-5, Anti-Reticulon-4, Anti-Nogo protein, Anti-Neurite outgrowth inhibitor, Anti-Neuroendocrine-specific protein, Anti-Neuroendocrine-specific protein C homolog |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-DD3 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | 23 amino acid synthetic peptide from near the N-terminus of human NogoA. |
Format: | Purified |
Database Information
KEGG ID : | K20720 | Matching products |
UniProt ID : | Q9NQC3 | Matching products |
Gene ID | GeneID 57142 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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