Anti-NOD1 / CARD4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59215.50	50 µg		-	-	6 - 14 business days*		551.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2... more

Close menu

Product information "Anti-NOD1 / CARD4"

Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection. [The UniProt Consortium]

Keywords:	Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization domain-containing protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59215

Properties

Application:	ICC, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	Recombinant protein corresponding to M1-M160 of Human NOD1 / CARD4
MW:	108 kD
Format:	Antigen Affinity Purified