Anti-NOD1 / CARD4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59175.100	100 µl		-	-	6 - 14 business days*		616.00€

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Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2... more

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Product information "Anti-NOD1 / CARD4"

Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection. [The UniProt Consortium]

Keywords:	Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization domain-containing protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59175

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 923-951 of Human NOD1
MW:	108 kD
Format:	Purified