Anti-NLRP7

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-RQ6892	100 µg		-	-	3 - 10 business days*		790.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. NACHT, LRR and PYD domains-containing... more

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Product information "Anti-NLRP7"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein function: Inhibits CASP1/caspase-1-dependent IL1B secretion. [The UniProt Consortium]

Keywords:	Anti-NLRP7, Anti-NALP7, Anti-PYRIN-containing APAF1-like protein 3, Anti-NACHT, LRR and PYD domains-containing protein 7, Anti-Nucleotide-binding oligomerization domain protein 12, NLRP7 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	RQ6892

Properties

Application:	WB, IHC (paraffin), FC, Direct ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant human protein (amino acids M1-L169)
Format:	Apoptosis, Cell Cycle, DNA Repair