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This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein function: Inhibits CASP1/caspase-1-dependent IL1B secretion. [The UniProt Consortium]
Keywords:
Anti-NALP7, Anti-NLRP7, Anti-PYRIN-containing APAF1-like protein 3, Anti-NACHT, LRR and PYD domains-containing protein 7, Anti-Nucleotide-binding oligomerization domain protein 12, NLRP7 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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