Anti-NLRP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA021183.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA021183.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK... more

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Product information "Anti-NLRP2"

Protein function: Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 53% and to rat: 49%

Keywords:	Anti-NALP2, Anti-NLRP2, Anti-Nucleotide-binding site protein 1, Anti-PYRIN-containing APAF1-like protein 2, Anti-NACHT, LRR and PYD domains-containing protein 2, Anti-PYRIN domain and NACHT domain-containing protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA021183

Properties

Application:	WB, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VDVVPSSFCV KHCRNLQKMS LQVIKENLPE NVTASESDAE VERSQDDQHM LPFWTDLCSI FGSNKDLMGL AINDSFLSAS LVRILCEQ (ATA-APrEST89238)