Anti-NLRC4

Anti-NLRC4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32329 100 µg - -

3 - 10 business days*

549.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NLR family CARD domain-containing protein... more
Product information "Anti-NLRC4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. Protein function: Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis. [The UniProt Consortium]
Keywords: Anti-Ipaf, Anti-NLRC4, Anti-CARD12, Anti-Clan protein, Anti-Ice protease-activating factor, Anti-CARD, LRR, and NACHT-containing protein, Anti-NLR family CARD domain-containing protein 4, Anti-Caspase recruitment domain-containing protein 12, NLRC4 Antibo
Supplier: NSJ Bioreagents
Supplier-Nr: R32329

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Amino acids KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR of human NLRC4/CARD12 were used as the immunogen for the NLRC4 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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