Anti-NKp30 (human), Unconjugated Clone B-S30 [Mouse]

Specificity: Recognises both natural and recombinant NKp30, Format: Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide, Working Dilution: Use 10 µl to label 106 cells or 100 µl of whole blood, Storage: Stable at +2-8°C for 12 months. For longer storage freeze aliquots, Application Notes: Suitable for Flow Cytometry Protein function: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. [The UniProt Consortium]