Anti-NIPA4

This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010], Protein function: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Sr(2+) and Fe(2+) but to a much less extent than Mg(2+). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway (PubMed:15317751). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Membrane , Multi-pass membrane protein .